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STAT4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24893N-1 50ul / $395
APR24893N-2 100ul / $495
APR24893N-3 200ul / $595

STAT4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24893N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>ErbB-HER Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STAT4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 85kDa Observed MW: 93kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human STAT4 (NP_001230764.1).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Synonyms

STAT4; SLEB11; signal transducer and activator of transcription 4

Images

Western blot analysis of extracts of various cell lines, using STAT4 antibody.

Specification

Quantity

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