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Caspase 9 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24892N-1 50ul / $395
APR24892N-2 100ul / $495
APR24892N-3 200ul / $595

Caspase 9 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24892N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Caspase 9 Polyclonal Antibody.

Molecular Weight

Calculated MW: 17kDa/30kDa/36kDa/46kDa Observed MW: 36kDa/46kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human Caspase 9

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Synonyms

CASP9; APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56; caspase-9

Images

Western blot analysis of extracts of various cell lines, using Caspase 9 antibody.

Western blot analysis of extracts of Jurkat cells, using Caspase 9 antibody.

Immunohistochemistry of paraffin-embedded rat lung using Caspase 9 Antibody.

Specification

Quantity

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