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APLP1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24891N-1 50ul / $395
APR24891N-2 100ul / $495
APR24891N-3 200ul / $595

APLP1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24891N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APLP1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 72kDa Observed MW: 65-70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human APLP1 (NP_005157.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Synonyms

APLP1; APLP; amyloid-like protein 1

Images

Western blot analysis of extracts of various cell lines, using APLP1 antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using APLP1 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using APLP1 antibody.

Specification

Quantity

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