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PLCG2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24700N-1 50ul / $395
APR24700N-2 100ul / $495
APR24700N-3 200ul / $595

PLCG2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24700N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLCG2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 147kDa Observed MW: 175kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PLCG2 (NP_002652.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100

Product Description

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Synonyms

PLCG2; APLAID; FCAS3; PLC-IV; PLC-gamma-2; phospholipase C gamma 2

Images

Western blot analysis of extracts of various cell lines, using PLCG2 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using PLCG2 antibody.

Immunofluorescence analysis of U2OS cells using PLCG2 antibody.

Specification

Quantity

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