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PLAU Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24699N-1 50ul / $395
APR24699N-2 100ul / $495
APR24699N-3 200ul / $595

PLAU Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24699N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLAU Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa/48kDa Observed MW: 49kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PLAU (NP_002649.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Synonyms

PLAU; ATF; BDPLT5; QPD; UPA; URK; u-PA; plasminogen activator, urokinase

Images

Western blot analysis of extracts of various cell lines, using PLAU antibody.

Specification

Quantity

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