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PDGFR beta Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24698N-1 50ul / $395
APR24698N-2 100ul / $495
APR24698N-3 200ul / $595

PDGFR beta Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24698N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDGFR beta Polyclonal Antibody.

Molecular Weight

Calculated MW: 37kDa/123kDa Observed MW: 200kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PDGFR beta (NP_002600.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Synonyms

PDGFRB; CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT; platelet-derived growth factor receptor beta

Images

Western blot analysis of extracts of various cell lines, using PDGFR beta antibody.

Immunofluorescence analysis of C6 cells using PDGFR beta antibody.

Immunofluorescence analysis of NIH/3T3 cells using PDGFR beta antibody.

Specification

Quantity

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