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BNP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24697N-1 50ul / $395
APR24697N-2 100ul / $495
APR24697N-3 200ul / $595

BNP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24697N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BNP Polyclonal Antibody.

Molecular Weight

Calculated MW: 14kDa Observed MW: 17kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human BNP (NP_002512.1).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.

Synonyms

NPPB; BNP; natriuretic peptide B

Images

Western blot analysis of extracts of rat heart, using BNP antibody.

Western blot analysis of extracts of mouse pancreas, using BNP antibody.

Specification

Quantity

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