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Ubiquitin Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24648N-1 50ul / $395
APR24648N-2 100ul / $495
APR24648N-3 200ul / $595

Ubiquitin Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24648N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Ubiquitin Polyclonal Antibody.

Molecular Weight

Calculated MW: 25kDa Observed MW: 17-110kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Ubiquitin (NP_061828.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

Synonyms

UBB; HEL-S-50; ubiquitin B

Images

Western blot analysis of extracts of various cell lines, using Ubiquitin antibody.

Specification

Quantity

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