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TYK2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24647N-1 50ul / $395
APR24647N-2 100ul / $495
APR24647N-3 200ul / $595

TYK2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24647N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>ErbB-HER Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TYK2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 133kDa Observed MW: 134kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human TYK2 (NP_003322.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Synonyms

TYK2; IMD35; JTK1; tyrosine kinase 2

Images

Western blot analysis of extracts of various cell lines, using TYK2 antibody.

Specification

Quantity

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