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PDE1B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24624N-1 50ul / $395
APR24624N-2 100ul / $495
APR24624N-3 200ul / $595

PDE1B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24624N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDE1B Polyclonal Antibody.

Molecular Weight

Calculated MW: 59kDa/61kDa Observed MW: 59kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PDE1B (NP_000915.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms

PDE1B; HEL-S-79p; PDE1B1; PDES1B; phosphodiesterase 1B

Images

Western blot analysis of extracts of various cell lines, using PDE1B antibody.

Immunohistochemistry of paraffin-embedded rat brain using PDE1B antibody.

Immunofluorescence analysis of U2OS cells using PDE1B antibody.

Specification

Quantity

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