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CYP27A1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24520N-1 50ul / $395
APR24520N-2 100ul / $495
APR24520N-3 200ul / $595

CYP27A1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24520N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Lipids

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP27A1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 60kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CYP27A1 (NP_000775.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.

Synonyms

CYP27A1; CP27; CTX; CYP27; sterol 26-hydroxylase, mitochondrial

Images

Western blot analysis of extracts of various cell lines, using CYP27A1 antibody.

Immunofluorescence analysis of HeLa cells using CYP27A1 antibody.

Specification

Quantity

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