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ACVR2A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24519N-1 50ul / $395
APR24519N-2 100ul / $495
APR24519N-3 200ul / $595

ACVR2A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24519N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Amino acid metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACVR2A Polyclonal Antibody.

Molecular Weight

Calculated MW: 45kDa/57kDa Observed MW: 57kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ACVR2A (NP_001607.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Synonyms

ACVR2A; ACTRII; ACVR2; activin receptor type-2A

Images

Western blot analysis of extracts of various cell lines, using ACVR2A antibody.

Immunohistochemistry of paraffin-embedded human lung using ACVR2A antibody.

Immunohistochemistry of paraffin-embedded human esophageal cancer using ACVR2A antibody.

Specification

Quantity

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