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CD27 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24487N-1 50ul / $395
APR24487N-2 100ul / $495
APR24487N-3 200ul / $595

CD27 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24487N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD27 Polyclonal Antibody.

Molecular Weight

Calculated MW: 29kDa Observed MW: 50-55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CD27 (NP_001233.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Synonyms

CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2; CD27 antigen

Images

Western blot analysis of extracts of various cell lines, using CD27 antibody.

Immunohistochemistry of paraffin-embedded rat spleen using CD27 antibody.

Immunohistochemistry of paraffin-embedded mouse spleen using CD27 antibody.

Specification

Quantity

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