> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CD27 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR24487N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Apoptosis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD27 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
29kDa
Observed MW:
50-55kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human CD27 (NP_001233.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
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Product Description |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
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Synonyms |
CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2; CD27 antigen
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Images |
Western blot analysis of extracts of various cell lines, using CD27 antibody.
Immunohistochemistry of paraffin-embedded rat spleen using CD27 antibody.
Immunohistochemistry of paraffin-embedded mouse spleen using CD27 antibody. |
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Specification |
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Quantity |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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