> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > APBB1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR24486N |
Product Type |
Polyclonal Antibodies | Field of Research |
Neuroscience>Neurodegenerative Diseases |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality APBB1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
49kDa/52kDa/53kDa/54kDa/76kDa/77kDa
Observed MW:
63kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human APBB1 (NP_663722.1).
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
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Product Description |
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Synonyms |
APBB1; FE65; MGC:9072; RIR; amyloid beta precursor protein binding family B member 1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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