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THPO Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24346N-1 50ul / $395
APR24346N-2 100ul / $495
APR24346N-3 200ul / $595

THPO Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24346N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality THPO Polyclonal Antibody.

Molecular Weight

Calculated MW: 33kDa/37kDa Observed MW: 32kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human THPO (NP_001171068.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Synonyms

THPO; MGDF; MKCSF; ML; MPLLG; THCYT1; TPO; thrombopoietin

Images

Western blot analysis of extracts of various cell lines, using THPO antibody.

Specification

Quantity

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