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CDC6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR24345N-1 50ul / $395
APR24345N-2 100ul / $495
APR24345N-3 200ul / $595

CDC6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR24345N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDC6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 62kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human CDC6.

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Synonyms

CDC18L; HsCDC6; MGORS5; HsCDC18

Images

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Specification

Quantity

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