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NACA Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17751N-1 50ul / $395
APR17751N-2 100ul / $495
APR17751N-3 200ul / $595

NACA Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17751N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NACA Polyclonal Antibody.

Molecular Weight

Calculated MW: 23kDa/94kDa/205kDa Observed MW: 37kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NACA (NP_001106673.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IP

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IP 1:50 - 1:100

Product Description

This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.

Synonyms

NACA; HSD48; NAC-alpha; NACA1; skNAC; nascent polypeptide-associated complex subunit alpha

Images

Western blot analysis of extracts of various cell lines, using NACA antibody.

Specification

Quantity

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