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MSH5 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17750N-1 50ul / $395
APR17750N-2 100ul / $495
APR17750N-3 200ul / $595

MSH5 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17750N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MSH5 Polyclonal Antibody.

Molecular Weight

Calculated MW: 91kDa/92kDa/93kDa/94kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MSH5 (NP_751897.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene.

Synonyms

MSH5; G7; MUTSH5; NG23; POF13; mutS homolog 5

Images

Western blot analysis of extracts of various cell lines, using MSH5 antibody.

Specification

Quantity

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