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CLC-5 Antibody

Catalog # Availability Size / Price Inquiry
APR11589G 50 μl / $695

CLC-5 Antibody

Brand

Leading Biology

Catalog Number

APR11589G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLC-5 antibody.

Molecular Weight

83068 Da

Host

Rabbit

Species Reactivity

Rat

Target

Peptide CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLC5??(Accession number P51796 ). Extracellular.

GeneID

UniProt ID

Summary

CLC5 is a member of the voltage-dependent Cl- channel family that includes nine known members. Basedon sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. Mutations in the CLC5 gene cause Dent's disease a X-linked renal disorder. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes vesicles, where it is believed to contribute to their acidification. The channel is mainly expressed in the kidney, although it has been found also in smallintestine, brain and liver.

Form

Affinity purified antibody, Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:200-1:2000

Synonyms

H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5, Clcn5

Images

Western blot analysis of rat kidney lysate: 1. Anti-CLC-5 antibody ( APR11589G), (1:200). 2. Anti-CLC-5 antibody, preincubated with the control peptide antigen.

Specification

Quantity

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