> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PPFIA3 AntibodyBrand |
Leading Biology | Catalog Number |
AMM07265G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPFIA3 antibody.
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Molecular Weight |
Predicted: 131 kDa Observed: 131 kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cell surface. Note=Colocalizes with PTPRF at the cell surface
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
PPFIA3; PPFIA3 antibody is human, mouse, and rat reactive.
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Isotype |
IgG
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Symbol |
KIAA0654
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GeneID |
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UniProt ID |
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Function |
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
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Summary |
The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development (1). Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones (2).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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