> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > COMMD7 AntibodyBrand |
Leading Biology | Catalog Number |
APR15543G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality COMMD7 antibody.
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Molecular Weight |
Predicted: 22 kDa Observed: 21 kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasmic vesicle
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
COMMD7; COMMD7 antibody is human, mouse and rat reactive. Multiple transcript variants encoding different isoforms have been found for COMMD7.
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Isotype |
IgG
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Symbol |
C20orf92
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GeneID |
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UniProt ID |
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Function |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966).
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Summary |
COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1). It associates with the NF-kB complex and suppresses its transcriptional activity (2). COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3). COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4). COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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