> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GBP6 AntibodyBrand |
Leading Biology | Catalog Number |
APR16106G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GBP6 antibody.
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Molecular Weight |
72427 Da
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Target |
GBP6; GBP6 antibody is predicted to not cross-react with other GBP family members.
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Function |
Binds GTP, GDP and GMP.
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Summary |
GBP6 Antibody: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IF, ICC, E
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Images |
Western blot analysis of GBP6 in Hela cell lysate with GBP6 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of GBP6 in HeLa cells with GBP6 antibody at 2.5 μg/mL.
Immunofluorescence of GBP6 in HeLa cells with GBP6 antibody at 5 μg/mL. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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