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GBP6 Antibody

Catalog # Availability Size / Price Inquiry
APR16106G 0.1 mg / $695

GBP6 Antibody

Brand

Leading Biology

Catalog Number

APR16106G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GBP6 antibody.

Molecular Weight

72427 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Target

GBP6; GBP6 antibody is predicted to not cross-react with other GBP family members.

Isotype

IgG

GeneID

UniProt ID

Function

Binds GTP, GDP and GMP.

Summary

GBP6 Antibody: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of GBP6 in Hela cell lysate with GBP6 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry of GBP6 in HeLa cells with GBP6 antibody at 2.5 μg/mL.

Immunofluorescence of GBP6 in HeLa cells with GBP6 antibody at 5 μg/mL.

Specification

Quantity

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