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MYBPC1 Antibody

Catalog # Availability Size / Price Inquiry
AMM06515G 0.1 mg / $695

MYBPC1 Antibody

Brand

Leading Biology

Catalog Number

AMM06515G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYBPC1 antibody.

Molecular Weight

128294 Da

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

MYBPC1; At least five isoforms of MYBPC1 are known to exist. MYBPC1 antibody is predicted not to cross-react with other MYBPC family members

Isotype

IgG

Symbol

MYBPCS

GeneID

UniProt ID

Function

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

Summary

MYBPC1 Antibody: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Images

Western blot analysis of MYBPC1 in rat skeletal muscle tissue lysate with MYBPC1 antibody at 1 μg/mL.

Immunofluorescence of MYBPC1 in mouse skeletal muscle cells with MYBPC1 antibody at 20 μg/mL.

Specification

Quantity

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