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AGTR1 Antibody

Catalog # Availability Size / Price Inquiry
APG01613G 0.1 mg / $695

AGTR1 Antibody

Brand

Leading Biology

Catalog Number

APG01613G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AGTR1 antibody.

Molecular Weight

41061 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

AGTR1;

Isotype

IgG

Symbol

AGTR1A, AGTR1B, AT2R1, AT2R1B

GeneID

UniProt ID

Function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.

Summary

AGTR1 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 μg/mL.

Immunofluorescence of AGTR1 in Mouse Kidney cells with AGTR1 antibody at 20 μg/mL.

Specification

Quantity

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