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PGCC1 Antibody

Catalog # Availability Size / Price Inquiry
AMM07115G 0.1 mg / $695

PGCC1 Antibody

Brand

Leading Biology

Catalog Number

AMM07115G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PGCC1 antibody.

Molecular Weight

103783 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

FAM120B; This antibody will not cross-react with FAM120A.

Isotype

IgG

Symbol

CCPG, KIAA1838

GeneID

UniProt ID

Function

Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity).

Summary

PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of PGCC1 in rat thymus tissue lysate with PGCC1 antibody at (A) 0.5 and (B) 1 μg/mL.

Specification

Quantity

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