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PSD-95 Antibody

Catalog # Availability Size / Price Inquiry
APR12997G 50 μl / $695

PSD-95 Antibody

Brand

Leading Biology

Catalog Number

APR12997G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSD-95 antibody.

Molecular Weight

80495 Da

Host

Rabbit

Species Reactivity

Human, Mouse

GeneID

UniProt ID

Summary

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

Form

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Synonyms

Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90, DLG4, PSD95

Images

Western blot analysis of rat brain synaptosomal fraction (lanes 1 and 3) and mouse brain lysate (lanes 2 and 4):1, 2. Anti-PSD-95antibody ( APR12997G), (1:200).3, 4. Anti-PSD-95 antibody, preincubated with the control peptide antigen.

Expression of PSD-95 in mouse parietal cortex Immunohistochemical staining of perfusion-fixed frozen mouse brain sections using Anti-PSD-95 antibody ( APR12997G), (1:400), followed by anti-rabbit-Cy3 antibody (red). Staining appears mainly in the pyramidal cell body (arrows). Nuclei were stained with DAPI (blue).

Specification

Quantity

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