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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Plexin-A2 (extracellular) Antibody

Plexin-A2 (extracellular) Antibody

Catalog # Availability Size / Price Inquiry
APR12899G 50 μl / $695

Plexin-A2 (extracellular) Antibody

Brand

Leading Biology

Catalog Number

APR12899G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Plexin-A2 (extracellular) antibody.

Molecular Weight

211535 Da

Host

Rabbit

Species Reactivity

Human, Mouse

GeneID

UniProt ID

Summary

Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm.

Form

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Synonyms

Plexin-A2, Plex 2, Plexin-2, Plxna2, Kiaa0463

Images

Western blot analysis of rat (lanes 1 and 3) and mouse brain membranes (lanes 2 and 4):1, 2. Anti-Plexin-A2 (extracellular) antibody ( APR12899G), (1:200).3, 4. Anti-Plexin-A2 (extracellular) antibody, preincubated with the control peptide antigen.

Immuno-colocalization of Plexin-A2 and p75NTR in rat brain Immunohistochemical staining of perfusion-fixed frozen rat brain sections using Anti-Plexin-A2 (extracellular) antibody ( APR12899G), (1:400) and mouse Anti-Rat p75NTR antibody ( AN-170), (1:300). A. Sections of rat horizontal diagonal band (HDB) were stained for Plexin-A2 (green). B. Same sections were stained for p75NTR (red). C. Merge of the two images reveals cells expressing both Plexin-A2 and p75NTR (horizontal arrows), cells expressing only Plexin-A2 (upwards pointing arrows) or cells expressing only p75NTR (downwards pointing arrows) can also be observed. Cell nuclei are stained with DAPI (blue).

Specification

Quantity

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