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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Phospho-Ser62,67 Synapsin I Antibody

Phospho-Ser62,67 Synapsin I Antibody

Catalog # Availability Size / Price Inquiry
APR12834G 100 μl / $545

Phospho-Ser62,67 Synapsin I Antibody

Brand

Leading Biology

Catalog Number

APR12834G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Ser62,67 Synapsin I antibody.

Molecular Weight

78 KDa

Host

Rabbit

Species Reactivity

Rat

Target

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 conjugated to KLH.

GeneID

UniProt ID

Summary

Synapsin I plays a key role in synaptic plasticity in brain (Feng et al.,2002; Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulatethe availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and insynaptogensis is regulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002). Ser 549along with Ser 62 and Ser 67 are the sites of Synapsin I that are phosphorylated by MAP kinase(Czernik et al., 1987; Jovanovic et al., 1996).

Form

Prepared from rabbit serum by affinity purification viasequential chromatography on phospho- and dephosphopeptide affinity columns.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~ 1:1000

Synonyms

Synapsin-1, Synapsin I, SYN1

Images

Western blot of rat cortex lysate showing specific labeling of the ~78k synapsin protein phosphorylated at Ser 62,67 (Control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown).

Specification

Quantity

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