> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Phospho-Ser549 Synapsin I AntibodyBrand |
Leading Biology | Catalog Number |
APR12821G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser549 Synapsin I antibody.
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Molecular Weight |
78 KDa
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Host |
Rabbit
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Species Reactivity |
Rat
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Target |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser549 conjugated to KLH.
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GeneID |
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UniProt ID |
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Summary |
Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002; Nayaket al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability ofsynaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated byphosphorylation (Jovanovic et al.,2001; Kao et al., 2002). Ser549along with Ser62and Ser67are the sites ofsynapsin I that are phosphorylated by MAP kinase (Jovanovic et al., 1996). Phosphorylation and subsequentdephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking.
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Form |
Prepared from rabbit serum by affinity purification via sequentialchromatography on phospho- and dephospho-peptide affinity columns. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC
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Dilution |
WB~~ 1:1000
IHC~~ 1:500
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Synonyms |
Synapsin-1, Synapsin I, SYN1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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