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BCL2 / Bcl-2 Antibody (aa46-95)

Catalog # Availability Size / Price Inquiry
APG02236G 50 μl / $495

BCL2 / Bcl-2 Antibody (aa46-95)

Brand

Leading Biology

Catalog Number

APG02236G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BCL2 / Bcl-2 antibody (aa46-95).

Molecular Weight

26kDa

Cellular Localization

Antigen Cellular Localization: Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

BCL-2 (Ab-69) Antibody detects endogenous levels of total BCL-2 protein.

GeneID

UniProt ID

Function

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Summary

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

ELISA (1:10000), IF (1:100-1:500), IHC-P (1:100), WB (1:500-1:1000) ,

Synonyms

Apoptosis regulator Bcl-2, BCL2

Images

Immunofluorescence of HepG2 cells, using BCL-2 (Ab-69) Antibody.

Western blot of extracts from K562 cells, using BCL-2 (Ab-69) Antibody.

Anti-BCL2 / Bcl-2 antibody IHC of human kidney, tubules.

Specification

Quantity

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