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HSD11B1 / HSD11B Antibody

Catalog # Availability Size / Price Inquiry
APR07799G 50 μl / $495

HSD11B1 / HSD11B Antibody

Brand

Leading Biology

Catalog Number

APR07799G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HSD11B1 / HSD11B antibody.

Molecular Weight

32kDa

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

This Polyclonal antibody is directed against human 11-Hydroxysteroid Dehydrogenase(Type 1)protein. The product was purified from serum by protein A chromatography. Expect reactivity with human 11-Hydroxysteroid Dehydrogenase(Type 1). Cross-reactivity ...

Symbol

HSD11, HSD11L

GeneID

UniProt ID

Function

Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity).

Summary

Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity).

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (1:100), WB (1:500-1:3000),

Synonyms

Corticosteroid 11-beta-dehydrogenase isozyme 1, 1.1.1.146, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11-beta-HSD1, HSD11B1, HSD11, HSD11L

Images

Anti-HSD11B1 antibody IHC of human lung, macrophages.

Specification

Quantity

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