> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ACTA1/α-actin Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM08742G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ACTA1/α-actin antibody (C-term).
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Molecular Weight |
H=42;M=42;Rat=42 KDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
346-375 aa
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Target |
This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human ACTA1/Alpha-actin.
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Symbol |
ACTA
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GeneID |
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UniProt ID |
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Function |
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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Summary |
The product encoded by this gene belongs to the actinfamily of proteins, which are highly conserved proteins that play arole in cell motility, structure and integrity. Alpha, beta andgamma actin isoforms have been identified, with alpha actins beinga major constituent of the contractile apparatus, while beta andgamma actins are involved in the regulation of cell motility. Thisactin is an alpha actin that is found in skeletal muscle. Mutationsin this gene cause nemaline myopathy type 3, congenital myopathywith excess of thin myofilaments, congenital myopathy with cores,and congenital myopathy with fiber-type disproportion, diseasesthat lead to muscle fiber defects.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, FC
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
IF~~1:10~50
FC~~1:10~50
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Synonyms |
ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-actin-1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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