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ITA6 Antibody

Catalog # Availability Size / Price Inquiry
APR17797G 100 μl / $495

ITA6 Antibody

Brand

Leading Biology

Catalog Number

APR17797G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITA6 antibody.

Molecular Weight

H=127,122,119,124,10 KDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein Cell membrane; Lipid-anchor

Host

Rabbit

Species Reactivity

Human

Immunogen

53-329 aa

Target

This ITA6 antibody is generated from rabbits immunized with ITA6 recombinant protein.

GeneID

UniProt ID

Function

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.

Summary

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~ 1:1000

Synonyms

ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD_antigen=CD49f; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain

Images

Western blot analysis of lysates from A431 cell line and human placenta tissue (from left to right), using ITA6 Antibody(Cat. APR17797G). APR17797G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.

Specification

Quantity

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