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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-DYX1C1 / EKN1 Antibody

Goat Anti-DYX1C1 / EKN1 Antibody

Catalog # Availability Size / Price Inquiry
APR12090G 0.1 mg / $495

Goat Anti-DYX1C1 / EKN1 Antibody

Brand

Leading Biology

Catalog Number

APR12090G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-DYX1C1 / EKN1 antibody.

Molecular Weight

48527 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

EKN1

GeneID

UniProt ID

Function

Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility.

Summary

This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Dyslexia susceptibility 1 candidate gene 1 protein, DYX1C1, EKN1

Images

APR12090G (0.5 μg/ml) staining of Human Brain (Frontal Cortex) lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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