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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-DYX1C1 (Isoform a) Antibody

Goat Anti-DYX1C1 (Isoform a) Antibody

Catalog # Availability Size / Price Inquiry
APG03361G 0.1 mg / $495

Goat Anti-DYX1C1 (Isoform a) Antibody

Brand

Leading Biology

Catalog Number

APG03361G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-DYX1C1 (Isoform a) antibody.

Molecular Weight

48527 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

EKN1

GeneID

UniProt ID

Function

Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility.

Summary

This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

Dyslexia susceptibility 1 candidate gene 1 protein, DYX1C1, EKN1

Images

APG03361G staining (0.1 μg/ml) of COS1 cell lysates: untransfected (left lane) and transfected with full length recombinant Human DYX1C1 (right lane). Data kindly provided by Wang and LoTurco, University of Connecticut, USA.

APG03361G (5 μg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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