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ECE-1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR07637G 100 μl / $495

ECE-1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR07637G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ECE-1 antibody (C-term).

Molecular Weight

87164 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

528-556 aa

Target

This ECE-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-556 amino acids from the C-terminal region of human ECE-1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Converts big endothelin-1 to endothelin-1.

Summary

ECE-1 is involved in proteolytic processing of endothelin precursors to biologically active peptides.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Endothelin-converting enzyme 1, ECE-1, ECE1

Images

Western blot analysis of ECE-1 Antibody (C-term) (Cat. APR07637G) in A2058 cell line lysates (35ug/lane). ECE-1 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human skin tissue reacted with ECE-1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

ECE-1 Antibody (C-term) (Cat. APR07637G) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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