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PAOX Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR17750G 100 μl / $495

PAOX Antibody (Center)

Brand

Leading Biology

Catalog Number

APR17750G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAOX antibody (Center).

Molecular Weight

70290 Da

Cellular Localization

Antigen Cellular Localization: Peroxisome. Cytoplasm

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

467-496 aa

Target

This PAOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-496 amino acids from the Central region of human PAOX.

Isotype

Rabbit Ig

Symbol

PAO

GeneID

UniProt ID

Function

Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase, PAOX, PAO

Images

PAOX Antibody (Center) (Cat. APR17750G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAOX antibody detected the PAOX protein (arrow).

PAOX Antibody (Center) (Cat. APR17750G) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PAOX antibody detected the PAOX protein (arrow).

PAOX antibody (Center) (Cat. APR17750G) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAOX antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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