> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > AVP Antibody (Center)Brand |
Leading Biology | Catalog Number |
APG03184G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AVP antibody (Center).
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Molecular Weight |
17325 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
102-129 aa
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Target |
This AVP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-129 amino acids from the Central region of human AVP.
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Isotype |
Rabbit Ig
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Symbol |
ARVP, VP
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GeneID |
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UniProt ID |
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Function |
Neurophysin 2 specifically binds vasopressin.
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Summary |
This gene encodes a precursor protein consisting ofarginine vasopressin and two associated proteins, neurophysin 2 anda glycopeptide, copeptin. Arginine vasopressin is a posteriorpituitary hormone which is synthesized in the supraoptic nucleusand paraventricular nucleus of the hypothalamus. Along with itscarrier protein, neurophysin 2, it is packaged into neurosecretoryvesicles and transported axonally to the nerve endings in theneurohypophysis where it is either stored or secreted into thebloodstream. The precursor is thought to be activated while it isbeing transported along the axon to the posterior pituitary.Arginine vasopressin acts as a growth factor by enhancing pHregulation through acid-base transport systems. It has a directantidiuretic action on the kidney, and also causes vasoconstrictionof the peripheral vessels. This hormone can contract smooth muscleduring parturition and lactation. It is also involved in cognition,tolerance, adaptation and complex sexual and maternal behaviour, aswell as in the regulation of water excretion and cardiovascularfunctions.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
IF~~1:10~50
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Synonyms |
Vasopressin-neurophysin 2-copeptin, AVP-NPII, Arg-vasopressin, Arginine-vasopressin, Neurophysin 2, Neurophysin-II, Copeptin, AVP, ARVP, VP
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Images |
Anti-AVP Antibody (Center) at 1:1000 dilution + ZR-75-1 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 17 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
AVP Antibody (Center) (Cat. APG03184G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AVP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of AVP Antibody (Center)( APG03184G) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue). |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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