> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DDC Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR07526G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DDC antibody (N-term).
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Molecular Weight |
53926 Da
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
32-61 aa
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Target |
This DDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human DDC.
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Isotype |
Rabbit Ig
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Symbol |
AADC
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GeneID |
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UniProt ID |
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Function |
Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
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Summary |
This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IF, WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IF~~1:10~50
IHC-P~~1:50~100
FC~~1:10~50
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Synonyms |
Aromatic-L-amino-acid decarboxylase, AADC, DOPA decarboxylase, DDC, DDC, AADC
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Images |
Anti-DDC Antibody (N-term) at 1:1000 dilution + human kidney lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 54 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Confocal immunofluorescent analysis of DDC Antibody (N-term)( APR07526G) with HepG2 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
DDC Antibody (N-term) (Cat. APR07526G) western blot analysis in mouse liver,kidney tissue lysates (15ug/lane).This demonstrates the DDC antibody detected DDC protein (arrow). |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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