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DDC Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR07526G 100 μl / $495

DDC Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR07526G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DDC antibody (N-term).

Molecular Weight

53926 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

32-61 aa

Target

This DDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human DDC.

Isotype

Rabbit Ig

Symbol

AADC

GeneID

UniProt ID

Function

Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.

Summary

This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IF, WB, IHC-P, FC, E

Dilution

WB~~1:1000 IF~~1:10~50 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Aromatic-L-amino-acid decarboxylase, AADC, DOPA decarboxylase, DDC, DDC, AADC

Images

Anti-DDC Antibody (N-term) at 1:1000 dilution + human kidney lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 54 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Confocal immunofluorescent analysis of DDC Antibody (N-term)( APR07526G) with HepG2 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

DDC Antibody (N-term) (Cat. APR07526G) western blot analysis in mouse liver,kidney tissue lysates (15ug/lane).This demonstrates the DDC antibody detected DDC protein (arrow).

Specification

Quantity

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