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LSP1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR17255G 100 μl / $495

LSP1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR17255G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LSP1 antibody (Center).

Molecular Weight

37192 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Host

Rabbit

Species Reactivity

Human

Immunogen

108-134 aa

Target

This LSP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-134 amino acids from the Central region of human LSP1.

Isotype

Rabbit Ig

Symbol

WP34

GeneID

UniProt ID

Function

May play a role in mediating neutrophil activation and chemotaxis.

Summary

LSP1 is an intracellular F-actin bindingprotein. The protein is expressed in lymphocytes, neutrophils,macrophages, and endothelium and may regulate neutrophil motility,adhesion to fibrinogen matrix proteins, and transendothelialmigration. Alternative splicing results in multiple transcriptvariants encoding different isoforms.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Lymphocyte-specific protein 1, 47 kDa actin-binding protein, 52 kDa phosphoprotein, pp52, Lymphocyte-specific antigen WP34, LSP1, WP34

Images

All lanes : Anti-LSP1 Antibody (Center) at 1:8000 dilution Lane 1: Daudi whole cell lysate Lane 2: Ramos whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

LSP1 Antibody (Center) (Cat. APR17255G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the LSP1 antibody detected the LSP1 protein (arrow).

LSP1 Antibody (Center) (Cat. APR17255G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LSP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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