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PRDX6 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMR09505G 100 μl / $495

PRDX6 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMR09505G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRDX6 antibody (Center).

Molecular Weight

25035 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Lysosome. Cytoplasmic vesicle. Note=Also found in lung secretory organelles.

Host

Rabbit

Species Reactivity

Human

Immunogen

103-132 aa

Target

This PRDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human PRDX6.

Isotype

Rabbit Ig

Symbol

AOP2, KIAA0106

GeneID

UniProt ID

Function

Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Summary

PRDX6 is a member of thethiol-specific antioxidant protein family. This protein is abifunctional enzyme with two distinct active sites. It is involvedin redox regulation of the cell; it can reduce H(2)O(2) and shortchain organic, fatty acid, and phospholipid hydroperoxides. It mayplay a role in the regulation of phospholipid turnover as well asin protection against oxidative injury.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106

Images

PRDX6 Antibody (Center) (Cat. AMR09505G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PRDX6 antibody detected the PRDX6 protein (arrow).

PRDX6 Antibody (Center) (Cat. AMR09505G) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRDX6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

PRDX6 Antibody (Center) (Cat. AMR09505G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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