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PRDX6 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMR09524G 100 μl / $495

PRDX6 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMR09524G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRDX6 antibody (C-term).

Molecular Weight

25035 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Lysosome. Cytoplasmic vesicle. Note=Also found in lung secretory organelles.

Host

Rabbit

Species Reactivity

Human

Immunogen

197-224 aa

Target

This PRDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-224 amino acids from the C-terminal region of human PRDX6.

Isotype

Rabbit Ig

Symbol

AOP2, KIAA0106

GeneID

UniProt ID

Function

Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Summary

PRDX6is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106

Images

Western blot analysis of PRDX6 Antibody (C-term) (Cat. AMR09524G) in CEM cell line lysates (35ug/lane). PRDX6 (arrow) was detected using the purified Pab.

Western blot analysis of PRDX6 (arrow) using rabbit polyclonal PRDX6 Antibody (C-term) (RB20894). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRDX6 gene (Lane 2) .

Formalin-fixed and paraffin-embedded human brain tissue reacted with PRDX6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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