> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PRDX3 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMR09519G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRDX3 antibody (N-term).
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Molecular Weight |
27693 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
66-94 aa
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Target |
This PRDX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human PRDX3.
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Isotype |
Rabbit Ig
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Symbol |
AOP1
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GeneID |
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UniProt ID |
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Function |
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
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Summary |
PRDX3 is a protein with antioxidant function and is localized in the mitochondrion. This protein is involved in redox regulation of the cell and Protects radical-sensitive enzymes from oxidative damage by a radical-generating system.It Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Synonyms |
Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1
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Images |
Western blot analysis of PRDX3 Antibody (N-term) (Cat. AMR09519G) in NCI-H460,MDA-MB231,HepG2 cell line lysates (35ug/lane). PRDX3 (arrow) was detected using the purified Pab.(2ug/ml)
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PRDX3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Flow cytometric analysis of MDA-MB468 cells using PRDX3 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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