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MFN1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR08438G 100 μl / $495

MFN1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR08438G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MFN1 antibody (Center).

Molecular Weight

84100 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion outer membrane; Multi- pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

353-381 aa

Target

This MFN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-381 amino acids from the Central region of human MFN1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

Summary

The protein encoded by this gene is a mediator ofmitochondrial fusion. This protein and mitofusin 2 are homologs ofthe Drosophila protein fuzzy onion (Fzo). They are mitochondrialmembrane proteins that interact with each other to facilitatemitochondrial targeting.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Mitofusin-1, 365-, Fzo homolog, Transmembrane GTPase MFN1, MFN1

Images

MFN1 Antibody (Center) (Cat. APR08438G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MFN1 antibody detected the MFN1 protein (arrow).

Specification

Quantity

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