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P2RX2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR08898G 100 μl / $495

P2RX2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR08898G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality P2RX2 antibody (N-term).

Molecular Weight

51754 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein Note=Localizes to the apical membranes of hair cells in the organ of Corti

Host

Rabbit

Species Reactivity

Human

Immunogen

81-109 aa

Target

This P2RX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human P2RX2.

Isotype

Rabbit Ig

Symbol

P2X2

GeneID

UniProt ID

Function

Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.

Summary

The product of this gene belongs to the family ofpurinoceptors for ATP. This receptor functions as a ligand-gatedion channel. Binding to ATP mediates synaptic transmission betweenneurons and from neurons to smooth muscle. Six transcript variantsencoding six distinct isoforms have been identified for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

P2X purinoceptor 2, P2X2, ATP receptor, Purinergic receptor, P2RX2, P2X2

Images

P2RX2 Antibody (N-term) (Cat. APR08898G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P2RX2 antibody detected the P2RX2 protein (arrow).

Specification

Quantity

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