> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PFN2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07111G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PFN2 antibody (C-term).
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Molecular Weight |
15046 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
110-139 aa
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Target |
This PFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of human PFN2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
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Summary |
The protein encoded by this gene is a ubiquitous actinmonomer-binding protein belonging to the profilin family. It isthought to regulate actin polymerization in response toextracellular signals. There are two alternatively splicedtranscript variants encoding different isoforms described for thisgene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Profilin-2, Profilin II, PFN2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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