> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BAG2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR07076G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BAG2 antibody (C-term).
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Molecular Weight |
23772 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
148-176 aa
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Target |
This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
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Summary |
BAG proteins compete with Hip for binding to theHsc70/Hsp70 ATPase domain and promote substrate release. All theBAG proteins have an approximately 45-amino acid BAG domain nearthe C terminus but differ markedly in their N-terminal regions. Thepredicted BAG2 protein contains 211 amino acids. The BAG domains ofBAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPasedomain in vitro and in mammalian cells. All 3 proteins bind withhigh affinity to the ATPase domain of Hsc70 and inhibit itschaperone activity in a Hip-repressible manner. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, BAG2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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