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AVPR1B Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR11474G 100 μl / $495

AVPR1B Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR11474G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AVPR1B antibody (C-term).

Molecular Weight

46971 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

289-317 aa

Target

This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.

Isotype

Rabbit Ig

Symbol

AVPR3, VPR3

GeneID

UniProt ID

Function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.

Summary

The protein encoded by this gene acts as receptor forarginine vasopressin. This receptor belongs to the subfamily ofG-protein coupled receptors which includes AVPR1A, V2R and OXTreceptors. Its activity is mediated by G proteins which stimulate aphosphatidylinositol-calcium second messenger system. The receptoris primarily located in the anterior pituitary, where it stimulatesACTH release. It is expressed at high levels in ACTH-secretingpituitary adenomas as well as in bronchial carcinoids responsiblefor the ectopic ACTH syndrome. A spliced antisense transcript ofthis gene has been reported but its function is not known.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3

Images

All lanes : Anti-AVPR1B Antibody (C-term) at 1:1000 dilution Lane 1: HUVEC whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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