> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NOSTRIN Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM06754G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NOSTRIN antibody (Center).
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Molecular Weight |
57660 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle Cytoplasm, cytoskeleton. Note=Enriched in selected actin structures
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
296-325 aa
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Target |
This NOSTRIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human NOSTRIN.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
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Summary |
Nitric oxide (NO) is a potent mediator in biologicprocesses such as neurotransmission, inflammatory response, andvascular homeostasis. NOSTRIN binds the enzyme responsible for NOproduction, endothelial NO synthase (ENOS; MIM 163729), andtriggers the translocation of ENOS from the plasma membrane tovesicle-like subcellular structures, thereby attenuatingENOS-dependent NO production.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Nostrin, BM247 homolog, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, eNOS-trafficking inducer, NOSTRIN
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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