> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > POF1B Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM07259G |
Product Type |
Polyclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality POF1B antibody (Center).
|
||
Molecular Weight |
68065 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Cell junction, tight junction
|
||
Host |
Rabbit
|
||
Species Reactivity |
Mouse
|
||
Immunogen |
337-366 aa
|
||
Target |
This POF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the Central region of human POF1B.
|
||
Isotype |
Rabbit Ig
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development.
|
||
Summary |
Premature ovarian failure (POF) is characterized byprimary or secondary amenorrhea in women less than 40 years old.Two POF susceptibility regions called 'POF1' and 'POF2' have beenidentified by breakpoint mapping of X-autosome translocations. POF1extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1.This gene, POF1B, resides in the POF2 region. This gene isexpressed at trace levels in mouse prenatal ovary and is barelydetectable or absent from adult ovary, in human and in the mouserespectively. This gene's expression is restricted to epitheliawith its highest expression in the epidermis, and oro-pharyngealand gastro-intestinal tracts. The protein encoded by this genebinds non-muscle actin filaments. The role this gene may play inthe etiology of premature ovarian failure remains to be determined.
|
||
Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, E
|
||
Dilution |
WB~~1:1000
|
||
Synonyms |
Protein POF1B, Premature ovarian failure protein 1B, POF1B
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 3 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
